With Drupal < 10.2 al works well with bigpipe.
After the upgrade to 10.2 i see some javascripts of mine that are not working, but only for registerer users.
These javascripts only trigger when there are no more [data-big-pipe-placeholder-id] in the DOM, and now there are some, and not always the same.
Examples of this bigpipes elements:
<span data-big-pipe-placeholder-id="callback=Drupal%5CCore%5CRender%5CElement%5CStatusMessages%3A%3ArenderMessages&args%5B0%5D&token=_HAdUpwWmet0TOTe2PSiJuMntExoshbm1kh2wQzzzAA">
</span>
<span data-big-pipe-placeholder-id="callback=Drupal%5Cgin%5CGinUserPicture%3Abuild&&token=s98iCtWwgE-Yk96QUBN6ff40MSZNc6oMcVwzrXgzV-Q">
</span>
If i disable bigpipe all works well again but it is not a good solution.
Php 8.1
Mariadb 10.4
No errors in screen or logs