Original report by adubovskoy
Existing drupal 8 site (upgraded from 8.2.x to 8.3, 8.4, 8.5). Current version 8.5.5 . If I enable layout_builder, then:
Error: Call to a member function getLabel() on null in Drupal\layout_builder\Plugin\Derivative\FieldBlockDeriver->getDerivativeDefinitions() (line 111 of /home/agwophqf/public_html/core/modules/layout_builder/src/Plugin/Derivative/FieldBlockDeriver.php) #0 /home/agwophqf/public_html/core/lib/Drupal/Component/Plugin/Discovery/DerivativeDiscoveryDecorator.php(101): Drupal\layout_builder\Plugin\Derivative\FieldBlockDeriver->getDerivativeDefinitions(Array) #1 /home/agwophqf/public_html/core/lib/Drupal/Component/Plugin/Discovery/DerivativeDiscoveryDecorator.php(87): Drupal\Component\Plugin\Discovery\DerivativeDiscoveryDecorator->getDerivatives(Array) #2 /home/agwophqf/public_html/core/lib/Drupal/Core/Plugin/DefaultPluginManager.php(284): Drupal\Component\Plugin\Discovery\DerivativeDiscoveryDecorator->getDefinitions() #3 /home/agwophqf/public_html/core/lib/Drupal/Core/Plugin/DefaultPluginManager.php(175): Drupal\Core\Plugin\DefaultPluginManager->findDefinitions() #4 /home/agwophqf/public_html/core/lib/Drupal/Component/Plugin/Discovery/DiscoveryCachedTrait.php(22): Drupal\Core\Plugin\DefaultPluginManager->getDefinitions() #5 /home/agwophqf/public_html/core/lib/Drupal/Core/Plugin/Factory/ContainerFactory.php(16): Drupal\Core\Plugin\DefaultPluginManager->getDefinition('system_main_blo...') #6 /home/agwophqf/public_html/core/lib/Drupal/Component/Plugin/PluginManagerBase.php(76): Drupal\Core\Plugin\Factory\ContainerFactory->createInstance('system_main_blo...', Array) #7 /home/agwophqf/public_html/core/lib/Drupal/Core/Plugin/DefaultSingleLazyPluginCollection.php(62): Drupal\Component\Plugin\PluginManagerBase->createInstance('system_main_blo...', Array) #8 /home/agwophqf/public_html/core/modules/block/src/BlockPluginCollection.php(57): Drupal\Core\Plugin\DefaultSingleLazyPluginCollection->initializePlugin('system_main_blo...') #9 /home/agwophqf/public_html/core/lib/Drupal/Component/Plugin/LazyPluginCollection.php(80): Drupal\block\BlockPluginCollection->initializePlugin('system_main_blo...') #10 /home/agwophqf/public_html/core/modules/block/src/BlockPluginCollection.php(45): Drupal\Component\Plugin\LazyPluginCollection->get('system_main_blo...') #11 /home/agwophqf/public_html/core/lib/Drupal/Core/Plugin/DefaultSingleLazyPluginCollection.php(83): Drupal\block\BlockPluginCollection->get('system_main_blo...') #12 /home/agwophqf/public_html/core/lib/Drupal/Core/Plugin/DefaultSingleLazyPluginCollection.php(99): Drupal\Core\Plugin\DefaultSingleLazyPluginCollection->setConfiguration(Array) #13 /home/agwophqf/public_html/core/lib/Drupal/Core/Plugin/DefaultSingleLazyPluginCollection.php(55): Drupal\Core\Plugin\DefaultSingleLazyPluginCollection->addInstanceId('system_main_blo...', Array) #14 /home/agwophqf/public_html/core/modules/block/src/BlockPluginCollection.php(34): Drupal\Core\Plugin\DefaultSingleLazyPluginCollection->__construct(Object(Drupal\Core\Block\BlockManager), 'system_main_blo...', Array) #15 /home/agwophqf/public_html/core/modules/block/src/Entity/Block.php(149): Drupal\block\BlockPluginCollection->__construct(Object(Drupal\Core\Block\BlockManager), 'system_main_blo...', Array, 'bone_content') #16 /home/agwophqf/public_html/core/modules/block/src/Entity/Block.php(138): Drupal\block\Entity\Block->getPluginCollection() #17 /home/agwophqf/public_html/core/modules/block/src/BlockAccessControlHandler.php(113): Drupal\block\Entity\Block->getPlugin() #18 /home/agwophqf/public_html/core/lib/Drupal/Core/Entity/EntityAccessControlHandler.php(105): Drupal\block\BlockAccessControlHandler->checkAccess(Object(Drupal\block\Entity\Block), 'view', Object(Drupal\Core\Session\AccountProxy)) #19 /home/agwophqf/public_html/core/lib/Drupal/Core/Entity/Entity.php(366): Drupal\Core\Entity\EntityAccessControlHandler->access(Object(Drupal\block\Entity\Block), 'view', Object(Drupal\Core\Session\AccountProxy), true) #20 /home/agwophqf/public_html/core/modules/block/src/BlockRepository.php(56): Drupal\Core\Entity\Entity->access('view', NULL, true) #21 /home/agwophqf/public_html/core/modules/block/src/Plugin/DisplayVariant/BlockPageVariant.php(137): Drupal\block\BlockRepository->getVisibleBlocksPerRegion(Array) #22 /home/agwophqf/public_html/core/lib/Drupal/Core/Render/MainContent/HtmlRenderer.php(259): Drupal\block\Plugin\DisplayVariant\BlockPageVariant->build() #23 /home/agwophqf/public_html/core/lib/Drupal/Core/Render/MainContent/HtmlRenderer.php(117): Drupal\Core\Render\MainContent\HtmlRenderer->prepare(Array, Object(Symfony\Component\HttpFoundation\Request), Object(Drupal\Core\Routing\CurrentRouteMatch)) #24 /home/agwophqf/public_html/core/lib/Drupal/Core/EventSubscriber/MainContentViewSubscriber.php(90): Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object(Symfony\Component\HttpFoundation\Request), Object(Drupal\Core\Routing\CurrentRouteMatch)) #25 [internal function]: Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object(Symfony\Component\HttpKernel\Event\GetResponseForControllerResultEvent), 'kernel.view', Object(Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher)) #26 /home/agwophqf/public_html/core/lib/Drupal/Component/EventDispatcher/ContainerAwareEventDispatcher.php(111): call_user_func(Array, Object(Symfony\Component\HttpKernel\Event\GetResponseForControllerResultEvent), 'kernel.view', Object(Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher)) #27 /home/agwophqf/public_html/vendor/symfony/http-kernel/HttpKernel.php(156): Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object(Symfony\Component\HttpKernel\Event\GetResponseForControllerResultEvent)) #28 /home/agwophqf/public_html/vendor/symfony/http-kernel/HttpKernel.php(68): Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object(Symfony\Component\HttpFoundation\Request), 1) #29 /home/agwophqf/public_html/core/lib/Drupal/Core/StackMiddleware/Session.php(57): Symfony\Component\HttpKernel\HttpKernel->handle(Object(Symfony\Component\HttpFoundation\Request), 1, true) #30 /home/agwophqf/public_html/core/lib/Drupal/Core/StackMiddleware/KernelPreHandle.php(47): Drupal\Core\StackMiddleware\Session->handle(Object(Symfony\Component\HttpFoundation\Request), 1, true) #31 /home/agwophqf/public_html/core/modules/page_cache/src/StackMiddleware/PageCache.php(99): Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object(Symfony\Component\HttpFoundation\Request), 1, true) #32 /home/agwophqf/public_html/core/modules/page_cache/src/StackMiddleware/PageCache.php(78): Drupal\page_cache\StackMiddleware\PageCache->pass(Object(Symfony\Component\HttpFoundation\Request), 1, true) #33 /home/agwophqf/public_html/core/lib/Drupal/Core/StackMiddleware/ReverseProxyMiddleware.php(47): Drupal\page_cache\StackMiddleware\PageCache->handle(Object(Symfony\Component\HttpFoundation\Request), 1, true) #34 /home/agwophqf/public_html/core/lib/Drupal/Core/StackMiddleware/NegotiationMiddleware.php(52): Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object(Symfony\Component\HttpFoundation\Request), 1, true) #35 /home/agwophqf/public_html/vendor/stack/builder/src/Stack/StackedHttpKernel.php(23): Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object(Symfony\Component\HttpFoundation\Request), 1, true) #36 /home/agwophqf/public_html/core/lib/Drupal/Core/DrupalKernel.php(666): Stack\StackedHttpKernel->handle(Object(Symfony\Component\HttpFoundation\Request), 1, true) #37 /home/agwophqf/public_html/index.php(19): Drupal\Core\DrupalKernel->handle(Object(Symfony\Component\HttpFoundation\Request)) #38 {main}.